The Calling of Saints Peter and Andrew is a painting by the Italian Baroque master Caravaggio. It takes its theme from a passage in the Gospel of Matthew describing the moment when Christ called the two brothers Simon – later known as Peter – and Andrew, to be his disciples:
As Jesus walked by the Sea of Galilee, he saw two brothers, Simon, who is called Peter, and Andrew his brother, casting a net into the sea – for they were fishermen. And he said to them, "Follow me, and I will make you fishers of men." Immediately, they left their nets and followed him.
— Matthew 4:18–20
The painting shows a young, beardless Christ, leading the two much older-looking brothers. The more prominent of the brothers, presumably Simon, is holding a fish in his right hand. The edge of the canvas is rather damaged, but the central panel is in good condition. The presence of "incisions" into the ground of the canvas marking out St. Peter's ear and the eyes of Christ are typical of Caravaggio's technique. The painting appears to date from the height of Caravaggio's Roman period, c. 1603–06.